It has long been accepted that a gene's protein-coding information is contained in only one of its two DNA strands. But in 22 February Nature, Victor Corces and co-workers at the Department of Biology ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Researchers show how a DNA-binding protein can search the entire genome for its target sequence without getting held up on the way. The result contradicts our current understanding of gene regulation ...