The introduction of array comparative genome hybridization (CGH) into prenatal genetic diagnosis presents both challenges and controversy to the clinical cytogenetic community. The challenges are ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

In addition to the surprising revelation that our chromosomes harbor fewer genes than originally predicted, the Human Genome Project also unveiled that all individuals share approximately 99.9% of ...

In this study we addressed the question whether MDS with normal karyotype in chromosome banding analysis harbor cytogenetically cryptic gains or losses detectable by array CGH. A total of 520 patients ...